isavuconazole

Term ID

CHEBI:85979

Synonyms

• 4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}benzonitrile
• BAL 4815
• isavuconazol
• isavuconazole
• isavuconazolum

Definition

A 1,3-thiazole that is butan-2-ol which is substituted at positions 1, 2, and 3 by 1,2,4-triazol-1-yl, 2,5-difluorophenyl, and 4-(p-cyanophenyl)-1,3-thiazol-2-yl groups, respectively. It is an antifungal drug used for the treatment of invasive aspergillosis and invasive mucormycosis.

References

• cas:241479-67-4
• pubmed:25313209
• pubmed:25488140
• pubmed:25561337
• pubmed:25624327
• pubmed:25753636
• pubmed:25940222
• pubmed:25986029
• pubmed:26000646
• reaxys:9295730
• wikipedia.en:Isavuconazole

Ontology

ChEBI  ( EBI )