Search Ontology:
ChEBI

KN-93

Term ID
CHEBI:91460
Synonyms
  • KN 93
  • KN93
  • N-[2-({[(2E)-3-(4-chlorophenyl)prop-2-en-1-yl](methyl)amino}methyl)phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide
  • N-[2-[[3-(4-chlorophenyl)prop-2-enyl-methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide
Definition
A sulfonamide resulting from the formal condensation of p-methoxybenzenesulfonic acid with the anilino nitrogen of 2-(aminomethyl)-N-(2-hydroxyethyl)aniline in which the hydrogens of the primary amino group have been replaced by methyl and p-chlorocinnamyl groups. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent protein kinase II.
References
  • cas:139298-40-1
  • lincs.smallmolecule:LSM-42804
  • pubmed:10712242
  • pubmed:16368898
  • pubmed:1662507
  • pubmed:17457979
  • pubmed:22363408
  • pubmed:23983471
  • pubmed:24142712
  • pubmed:24829059
  • pubmed:24836181
  • pubmed:25206480
  • pubmed:25498987
  • pubmed:25937575
  • pubmed:26024774
  • pubmed:26463508
  • pubmed:9864285
  • reaxys:8359108
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from KN-93
Phenotype where environments contain KN-93
Phenotype modified by environments containing KN-93
Phenotype affecting KN-93
Human Disease Model