autoimmune lymphoproliferative syndrome

Term ID

DOID:6688

Synonyms

• ALPS
• Canale-Smith syndrome

Definition

A hypersensitivity reaction type IV disease that is an inherited disorder in which the body cannot properly regulate the number of immune system cells (lymphocytes). It is characterized by the production of an abnormally large number of lymphocytes. Accumulation of excess lymphocytes results in enlargement of the lymph nodes, the liver, and the spleen. http://ghr.nlm.nih.gov/condition/autoimmune-lymphoproliferative-syndrome

References

• GARD:8686
• ICD10CM:D89.82
• ICD9CM:279.41
• MESH:D056735
• MIM:601859
• NCI:C37864
• ORDO:3261
• SNOMEDCT_US_2023_03_01:702444009
• UMLS_CUI:C1328840

Ontology

Human Disease   ( DOID:6688 )