Search Ontology:
GO: Biological Process

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Term ID
GO:0000184
Synonyms
  • mRNA breakdown, nonsense-mediated decay
  • mRNA catabolic process, nonsense-mediated
  • mRNA catabolism, nonsense-mediated
  • mRNA degradation, nonsense-mediated decay
  • nonsense-mediated mRNA decay
  • nuclear mRNA catabolic process, nonsense-mediated decay
Definition
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. 10025395
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
Phenotype
Phenotype caused by Genes
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