aspartic-type endopeptidase activity

Term ID

GO:0004190

Synonyms

• aspartate protease activity
• aspartic endopeptidase activity
• aspartic protease activity
• aspartyl protease activity
• carboxyl protease activity

Definition

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. 0198506732

References

• EC:3.4.23.-
• EC:3.4.23.1
• EC:3.4.23.15
• EC:3.4.23.20
• EC:3.4.23.25
• EC:3.4.23.32
• EC:3.4.23.34
• EC:3.4.23.35
• EC:3.4.23.36
• EC:3.4.23.4
• EC:3.4.23.43
• EC:3.4.23.49
• EC:3.4.23.5
• MetaCyc:3.4.23.1-RXN
• MetaCyc:3.4.23.15-RXN
• MetaCyc:3.4.23.20-RXN
• MetaCyc:3.4.23.25-RXN
• MetaCyc:3.4.23.32-RXN
• MetaCyc:3.4.23.34-RXN
• MetaCyc:3.4.23.35-RXN
• MetaCyc:3.4.23.4-RXN
• MetaCyc:3.4.23.43-RXN
• MetaCyc:3.4.23.5-RXN
• Reactome:R-HSA-157353
• Reactome:R-HSA-157640
• Reactome:R-HSA-2022403
• Reactome:R-HSA-2022412
• Reactome:R-HSA-2065357
• Reactome:R-HSA-2220988
• Reactome:R-HSA-373705
• Reactome:R-HSA-9013361
• Reactome:R-HSA-9017817
• Reactome:R-HSA-9604294

Ontology

GO: Molecular Function    QuickGO    AmiGO