blood coagulation, extrinsic pathway

Term ID

GO:0007598

Synonyms

• initiation of blood coagulation cascade, tissue factor pathway

Definition

A protein activation cascade that initiates blood coagulation, starting with a signal from tissue factor (TF), a cell-surface, integral-membrane protein, which converts Factor IX to IXa, and Factor IXa converts Factor X to Xa. Factor Xa then initiates the common pathway. 26018600

References

• Reactome:R-HSA-140834

Ontology

GO: Biological Process    QuickGO    AmiGO