heparin proteoglycan catabolic process

Term ID

GO:0030211

Synonyms

• heparan sulfate catabolic process
• heparin breakdown
• heparin catabolism
• heparin degradation

Definition

The chemical reactions and pathways resulting in the breakdown of heparin proteoglycans, which consist of a core protein linked to a heparin glycosaminoglycan. The heparin chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups and the latter being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids. Heparin is similar to heparan sulfate but it contains more N-sulfate and O-sulfate groups. 35536982

References

Ontology

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