methyltransferase cap2 activity

Term ID

GO:0120550

Synonyms

• cap2-MTase activity
• mRNA (nucleoside-2'-O-)-methyltransferase activity

Definition

Catalysis of the reaction: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(ribonucleotide) in mRNA or snRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA or snRNA + S-adenosyl-L-homocysteine + H+. This activity catalyzes the methylation of the ribose on the second transcribed nucleotide of mRNAs and snRNAs. 2.1.1.296

References

• EC:2.1.1.296
• MetaCyc:RXN-14928

Ontology

GO: Molecular Function    QuickGO    AmiGO