Search Ontology:
GO: Molecular Function

histone H3K27 trimethyltransferase activity

Term ID
GO:0140951
Synonyms
  • histone H3-K27 trimethylase activity
  • histone H3-K27 trimethylation
  • histone H3K27 mono/di/trimethylase activity
  • histone H3K27 trimethylase activity
  • histone H3K27 trimethylation
  • histone lysine N-trimethyltransferase activity (H3-K27 specific)
Definition
Catalysis of the reaction: L-lysyl27-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl27-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me3.
References
  • RHEA:60292
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
Phenotype
Phenotype caused by Genes
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