negative regulation of pyruvate decarboxylation to acetyl-CoA

Term ID

GO:0160218

Synonyms

• negative regulation of acetyl-CoA biosynthetic process from pyruvate

Definition

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. In most organisms, this pathway links glycolysis to the TCA cycle, by a series of three reactions carried out by a multisubunit complex called the 'pyruvate dehydrogenase complex', even though pyruvate dehydrogenase activity describes only one of those reactions. (3)

References

Ontology

GO: Biological Process    QuickGO    AmiGO