Jon Clarke Lab

We are interested in the morphogenesis and regionalisation of the neural tube, the development of the neuroepithelium especially in terms of its apico-basal organisation and the way that neural progenitors generate the differentiated cell types of the brain. We use a variety of cell labeling techniques and live-imaging that allow us to follow the fate of either individual cells or populations of cells. In addition we are using calcium imaging and FRAP techniques to study cell-cell communication in the early neuroepithelium.