Laudet Lab

Our lab is studying the role of nuclear hormone receptors in developpement and evolution. We focuss on 4 main topics : (i) role of the estrogen receptors (ER) and the estrogen related receptors (ERR) which are orphan receptors in development ; (ii) the study of circadian rhythm using the zebrafish as a model system with a particular emphasis on the role of the orphan receptors Rev-erb and ROR ; (iii) the importance of gene duplications in vertebrate evolution, using the nuclear hormone receptors are markers and (iv) the evolution of thyroid hormone regulation of metamorphosis in vertebrates.