|
Phenotype
|
Fish
|
Conditions
|
Figures
|
|
whole organism fgg expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6 
from Capecki et al., 2026
|
|
whole organism itln2 expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism f7i expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism angptl3 expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism agt expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
palatoquadrate cartilage malformed, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
palatoquadrate cartilage Ab6-col2a1 labeling increased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
palatoquadrate cartilage Ab6-col2a1 labeling spatial pattern, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
whole organism prss1 expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism ecm1a expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism s100a10a expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism he1.1 expression increased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism serpinh1b expression increased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism c1qtnf9 expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism mbl2 expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism adamts13 expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism fga expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism serpina1 expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism cela1.6 expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism ebi3 expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism mep1a.2 expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
sternohyoid Ab1-ddr2 labeling decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
whole organism itih3b.1 expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism ctslb expression increased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
interhyal cartilage Ab1-ddr2 labeling decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
whole organism serpinf2a expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
hyohyoideus Ab1-ddr2 labeling spatial pattern, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
whole organism ctsbb expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism ins expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
hyohyoideus Ab1-ddr2 labeling decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
ethmoid cartilage Ab6-col2a1 labeling spatial pattern, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
whole organism lgals2b expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism tmprss15 expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
sternohyoid Ab1-ddr2 labeling spatial pattern, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
interhyal cartilage Ab1-ddr2 labeling spatial pattern, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
ethmoid cartilage shortened, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
whole organism prg4b expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism anxa2b expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
extracellular matrix assembly increased occurrence, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
ethmoid cartilage Ab6-col2a1 labeling decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
whole organism he1.2 expression increased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism mep1a.1 expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
whole organism fgb expression decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 6
from Capecki et al., 2026
|
|
cranial skeletal system development decreased process quality, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a
|
standard conditions
|
Figure 3
from Capecki et al., 2026
|
|
palatoquadrate cartilage Ab6-col2a1 labeling increased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a + MO1-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
palatoquadrate cartilage malformed, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a + MO1-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
palatoquadrate cartilage Ab6-col2a1 labeling spatial pattern, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a + MO1-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
sternohyoid Ab1-ddr2 labeling decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a + MO1-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
interhyal cartilage Ab1-ddr2 labeling decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a + MO1-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
hyohyoideus Ab1-ddr2 labeling spatial pattern, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a + MO1-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
hyohyoideus Ab1-ddr2 labeling decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a + MO1-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
ethmoid cartilage Ab6-col2a1 labeling spatial pattern, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a + MO1-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
sternohyoid Ab1-ddr2 labeling spatial pattern, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a + MO1-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
interhyal cartilage Ab1-ddr2 labeling spatial pattern, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a + MO1-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
ethmoid cartilage shortened, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a + MO1-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
ethmoid cartilage Ab6-col2a1 labeling decreased amount, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a + MO1-ddr2a
|
standard conditions
|
Figure 4
from Capecki et al., 2026
|
|
cranial skeletal system development decreased process quality, abnormal
|
WT + CRISPR1-ddr2a + CRISPR2-ddr2a + CRISPR3-ddr2a + CRISPR4-ddr2a + CRISPR5-ddr2a + MO1-ddr2a
|
standard conditions
|
Figure 3
from Capecki et al., 2026
|
