FIGURE

Fig. 2

ID

ZDB-FIG-111212-8

Publication

Yee et al., 2011 - Transient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg2+-sensitive Socs3a signaling in development and cancer

Other Figures

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Fig. 2

The swd^p75fm mutation impairs exocrine pancreatic epithelial cell division and cell growth. (A) Cell-cycle analysis of the exocrine pancreatic epithelia in swd^p75fm mutants and WT siblings at 72 hpf. % BrdU+ nuclei represent the proportion of cells in the S phase of the cell cycle. (B) Morphometric analysis of cell growth (area, in µm², per cell) in the exocrine pancreatic epithelia of swd^p75fm mutants and WT siblings on 3 and 5 dpf. Each value represents the mean + s.e.m. Statistical analysis was performed using Student’s t-test, with *P<0.05 considered statistically significant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	swd^p75fm/p75fm
Observed In:	epithelial cell of pancreas epithelial cell proliferation mitotic cell cycle
Stage Range:	Protruding-mouth to Day 5

Phenotype Detail

Acknowledgments

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