FIGURE

Fig. S1

ID

ZDB-FIG-120118-10

Publication

Bhat et al., 2011 - Integrin-α5 Coordinates Assembly of Posterior Cranial Placodes in Zebrafish and Enhances Fgf-Dependent Regulation of Otic/Epibranchial Cells

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Fig. S1

Abnormal development of posterior placodes in itga5^b926/b926 mutants. (A, B) pax2a expression at 14 hpf in the otic/epibranchial domain in a wild-type embryo (A) and itga5 mutant (B). Otic placodes (o, brackets) are indicated. (C, D) neuroD expression at 14 hpf in a control embryo (C) and itga5 morphant (D). Precursors of the trigeminal ganglion (tg) and anterior lateral line (al) are indicated. (E, F) Immunolocalization of Pax2 (green) and Caspase 3 (red) in a wild-type embryo (E) and itga5 mutant (F). (G, H) Otic vesicles at 24hpf in a wild-type embryo (G) and itga5 mutant (H). (I, J) phox2a expression in epibranchial ganglia at 30 hpf in a wild-type embryo (I) and itga5 mutant (J). Facial (f), glossopharyngeal (g), and vagal ganglia (v1+v2) are indicated. A–E are dorsal views with anterior to the top; G–J are lateral views with anterior to the left. Scale bar, 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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