FIGURE
            Fig. S5
- ID
- ZDB-FIG-151110-24
- Publication
- D'Aniello et al., 2015 - Rdh10a Provides a Conserved Critical Step in the Synthesis of Retinoic Acid during Zebrafish Embryogenesis
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                        Fig. S5
                    
                    
                
                
            
        
        
    
        
            
            
| Comparison of ROL, RAL and RA teratogenicity from treatments beginning at the shield stage. (A-I) Embryos at 48 hpf that were treated from shield stage through 24 hpf with DMSO, ROL, RAL, and RA. (D,G) Low concentrations of RAL (0.1 µM) and ROL (10 µM) did not cause significant overt defects. (B,E,H) Intermediate concentrations of RAL (1 µM) and ROL (20 µM) and the lower concentration of RA (0.025 µM) produced truncated embryos that still had eyes (arrows). (C,F,I) 0.05 µM RA, 2 µM RAL, and 40 µM ROL produced severely truncated embryos with reduced eyes. | 
                
                    
                        Expression Data
                    
                    
                
                
            
        
        
    
        
            
            
            
            
    
    
                
                    
                        Expression Detail
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Antibody Labeling
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Phenotype Data
                    
                    
                
                
            
        
        
    
        
            
            
            
            
    
    
                
                    
                        Phenotype Detail
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Acknowledgments
                    
                    
                
                
            
        
        
    
        
            
            
                
                    
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      Full text @ PLoS One
                
                
            
        
        
    
    
     
        