FIGURE

Fig. S2

ID

ZDB-FIG-180611-43

Publication

Colombo et al., 2017 - nkx genes establish SHF cardiomyocyte progenitors at the arterial pole and pattern the venous pole through Isl1 repression

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Fig. S2

nkx genes regulate shox2

(A-E) Ventral view, anterior to the top, at 52 hpf illustrates in situ hybridization for shox2. Expression of shox2 is restricted to the IFT in wild-type (black arrow) (n = 11/13) (A) and nkx2.5^+/+;nkx2.7^-/- (n = 5/6) (B) embryos. However, its expression is expanded throughout the cardiac chambers in nkx2.5^-/-;nkx2.7^+/+ (n = 9/10) (C), nkx2.5^{- /-};nkx2.7^+/- (n = 12/13) (D), and nkx2.5^-/-;nkx2.7^-/- (n = 5/7) (E) embryos.

Expression Data

Gene:	shox2
Fish:	WT nkx2.5^vu179/vu179 nkx2.7^vu413/vu413 nkx2.5^vu179/vu179; nkx2.7^vu413/+ nkx2.5^vu179/vu179; nkx2.7^vu413/vu413
Anatomical Terms:	atrium cardiac ventricle myocardium sinus venosus
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nkx2.5^vu179/vu179 nkx2.5^vu179/vu179; nkx2.7^vu413/+ nkx2.5^vu179/vu179; nkx2.7^vu413/vu413
Observed In:	atrium cardiac ventricle myocardium
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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