FIGURE

Fig. S1

ID

ZDB-FIG-180906-38

Publication

Rolig et al., 2017 - The enteric nervous system promotes intestinal health by constraining microbiota composition

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Fig. S1

sox10 mutants experience delayed intestinal transit.

(A) Representative images of wild type (WT, left) and sox10^- (middle and right images) distal intestine. Anti-ElavI labeled enteric neurons are green (green arrow). Scale bar 100 mm. There are no enteric neurons in the sox10^- fish. (B) Schematic of the fluorescent food feeding schedule. Color indicates administration of fluorescent tracer; arrow indicates time of imaging for 8 dpf fish. (C) Representative images of 8 dpf wild types and sox10 mutants. Scale bar 100 mm. (D) The percent of fish with the indicated fluorescent food color in their intestines at 7 and 8 dpf (i.e. ‘eaters’). Each point represents the percentage of eaters from a separate dish of nine to 30 fish. In total, n > 200 fish per genotype per day. Bars represent mean ± SD. **** p < 0.0001, Student’s T-test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sox10^t3/t3
Observed In:	enteric neuron intestinal motility
Stage Range:	Day 5 to Days 7-13

Phenotype Detail

Acknowledgments

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