FIGURE

Fig. 5

ID

ZDB-FIG-210611-33

Publication

Griffin et al., 2021 - Phenotypic analysis of catastrophic childhood epilepsy genes

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Fig. 5

Distribution of ictal-like events.

Histograms depict number and duration of ictal events measured using a custom MATLAB-based program for a all sibling wild-type (WT) larvae from EZP epilepsy lines and b same for epileptic zebrafish lines (EZP)-Epi. Box-and-whisker plots showing the distribution of ictal event durations; mean and minimum/maximum values are shown (insets). c Estimation plot showing that ictal event duration for WT (1.134 ± 0.075 s; N = 56 larvae) is shorter than for Epi-EZP (1.353 ± 0.043 s; N = 299 larvae); Non-parametric t test *p = 0.0352, t = 2.115, df = 353). Each dot on the top plot represents the duration (measured in msec) for one individual ictal event. LFP recording epochs were 15 min. Data displayed as mean ± SEM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	arxa^s3005/s3005 eef1a2^s3012/s3012 gabrb3^s3015/s3015 grin1b^s3020/s3020 pnpo^s3028/s3028 scn1lab^s552/s552 strada^s3036/s3036 stxbp1b^s3038/s3038 grin1b^s3020/+
Observed In:	brain action potential
Stage:	Day 5

Phenotype Detail

Acknowledgments

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