FIGURE

Fig. 2

ID

ZDB-FIG-240328-73

Publication

Sebastian et al., 2024 - Cardiac manifestations of human ACTA2 variants recapitulated in a zebrafish model

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Fig. 2

Endogenous ACTA2 expression in the heart. Schematic figure of transversal section of zebrafish larvae Tg[cmlc2:EGFP] at 4 days post-fertilization. Immunostaining of 4dpf larvae Tg[cmlc2:EGFP] with anti-acta2 antibody (red), followed by 4’,6-diamidino-2-phenylindole (DAPI) co-staining (blue). A’ Brain region. B’ Heart region. Scale bar: 100 μm. A”, B” High magnification of immunostaining image. Scale bar: 20 μm. A” In the brain area, endogenous ACTA2 was not identified. B” In the heart area, endogenous ACTA2 was highly expressed, highlighted with EGFP green fluorescence, anti-acta2 antibody (red), and DAPI. Illustration of zebrafish was created with Biorender.com

Expression Data

Gene:	acta2
Antibody:	Ab7-acta2
Fish:	oi11Tg
Anatomical Term:	heart
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Hum. Genet.