FIGURE

Figure 4

ID

ZDB-FIG-250113-13

Publication

Licitra et al., 2025 - Trehalose Ameliorates Zebrafish Emotional and Social Deficits Caused by CLN8 Dysfunction

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Figure 4

Social preference test behavioral results before (A) and after (B) the trehalose treatment on cln8^−/− and WT fish (n = 10). Data are represented as individual values (lines indicate means ± SEM) and expressed in terms of cumulative duration. Statistical analyses showed impairments in sociality in cln8^−/− compared to WT before the trehalose feed supplementation (* p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001; **** p ≤ 0.0001). The images on the left are representative of the heatmap locomotor activity during the test; the range of color is from dark blue (low activity) to red (high activity).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cln8^irc2/irc2 (AB)
Condition:	chemical treatment by diet: trehalose
Observed In:	social behavior
Stage:	Adult

Phenotype Detail

Acknowledgments

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