FIGURE

Figure 1

ID

ZDB-FIG-251023-151

Publication

Hanot et al., 2025 - Ezh2 Loss-of-Function Alters Zebrafish Cerebellum Development

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Figure 1

Role of ezh2 in oligodendrocyte development: (A) whole-mount RNA in situ hybridization of the brain region of ezh2^+/+ and ezh2^−/− siblings at 2, 3 or 5 dpf, as indicated, to detect olig2 expression as a marker of the oligodendrocyte lineage; (B) whole-mount RNA in situ hybridization of the brain region of ezh2^+/+ and ezh2^−/− siblings at 5 dpf to detect mag or mpz expression, as markers of mature oligodendrocytes. Scale bar is 200 µm; and (C) schematic representation of zebrafish brain organization at 5 dpf. Olfactory bulbs are shown in green, the midline in red, and the cerebellum in blue.

Expression Data

Genes:	mag mpz olig2
Fish:	WT ezh2^ul2/ul2
Anatomical Terms:	cerebellum oligodendrocyte hindbrain oligodendrocyte midbrain oligodendrocyte
Stage Range:	Long-pec to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ezh2^ul2/ul2
Observed In:	oligodendrocyte development
Stage Range:	Long-pec to Day 5

Phenotype Detail

Acknowledgments

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