ZFIN is now using GRCz12tu for Genomic Data
Gene
bdnf
- ID
- ZDB-GENE-000412-1
- Name
- brain-derived neurotrophic factor
- Symbol
- bdnf Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable growth factor activity and nerve growth factor receptor binding activity. Acts upstream of or within circadian behavior; multicellular organismal response to stress; and nervous system development. Predicted to be active in several cellular components, including axon; dendrite; and synaptic vesicle. Is expressed in several structures, including blastoderm; digestive system; kidney; nervous system; and oral region. Human ortholog(s) of this gene implicated in several diseases, including cocaine dependence; cognitive disorder (multiple); congenital central hypoventilation syndrome; neurodegenerative disease (multiple); and obstructive sleep apnea. Orthologous to human BDNF (brain derived neurotrophic factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 99 figures from 52 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:76834 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Brain-derived neurotrophic factor | Cystine-knot cytokine | Nerve growth factor conserved site | Nerve growth factor-like | Nerve growth factor-related |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1P735 | InterPro | 278 | |||||
| UniProtKB:Q6NZ01 | InterPro | 270 | |||||
| UniProtKB:A0AB32TV83 | InterPro | 298 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers