pou4f1

ID

ZDB-GENE-000523-2

Name

POU class 4 homeobox 1

Symbol

pou4f1 Nomenclature History

Previous Names

brn3.0
brn3a (1)
brn3b-pen (1)
etID22526.1 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within heart development. Predicted to be located in nucleus. Is expressed in male organism; nervous system; and swim bladder. Orthologous to human POU4F1 (POU class 4 homeobox 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

20 figures from 14 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pou4f1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Ataxia, intention tremor, and hypotonia syndrome, childhood-onset	619352

Associated With pou4f1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR000327	POU-specific domain
Domain	IPR001356	Homeodomain
Domain	IPR013847	POU domain
Family	IPR050255	POU domain transcription factor
Homologous_superfamily	IPR009057	Homedomain-like superfamily
Homologous_superfamily	IPR010982	Lambda repressor-like, DNA-binding domain superfamily