ZFIN is now using GRCz12tu for Genomic Data
Gene
odc1
- ID
- ZDB-GENE-010816-1
- Name
- ornithine decarboxylase 1
- Symbol
- odc1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ornithine decarboxylase activity. Acts upstream of or within eye photoreceptor cell development. Predicted to be active in cytoplasm. Is expressed in neuromast and ovary. Orthologous to human ODC1 (ornithine decarboxylase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 19 figures from 18 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55204 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Bachmann-Bupp syndrome | 619075 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR022653 | Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site |
| Conserved_site | IPR022657 | Orn/DAP/Arg decarboxylase 2, conserved site |
| Domain | IPR022643 | Orn/DAP/Arg decarboxylase 2, C-terminal |
| Domain | IPR022644 | Orn/DAP/Arg decarboxylase 2, N-terminal |
| Family | IPR000183 | Ornithine/DAP/Arg decarboxylase |
| Family | IPR002433 | Ornithine decarboxylase |
| Homologous_superfamily | IPR009006 | Alanine racemase/group IV decarboxylase, C-terminal |
| Homologous_superfamily | IPR029066 | PLP-binding barrel |
Domain Details Per Protein
| Protein | Additional Resources | Length | Alanine racemase/group IV decarboxylase, C-terminal | Orn/DAP/Arg decarboxylase 2, conserved site | Orn/DAP/Arg decarboxylase 2, C-terminal | Orn/DAP/Arg decarboxylase 2, N-terminal | Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site | Ornithine/DAP/Arg decarboxylase | Ornithine decarboxylase | PLP-binding barrel |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q9DGJ4 | InterPro | 461 |
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-odc1 | monoclonal | IgG2b | Mouse |
|
Sigma-Aldrich
|
3 |
Plasmids
No data available
- Genome Browsers