ZFIN is now using GRCz12tu for Genomic Data
Gene
gnat1
- ID
- ZDB-GENE-011128-11
- Name
- guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
- Symbol
- gnat1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway; detection of light stimulus involved in visual perception; and phototransduction, visible light. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and visual perception. Predicted to be located in membrane. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in cytoplasm. Is expressed in head; pineal complex; and visual system. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1G; congenital stationary night blindness autosomal dominant 3; and night blindness. Orthologous to human GNAT1 (G protein subunit alpha transducin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 46 figures from 28 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73094 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital stationary night blindness 1G | Alliance | Night blindness, congenital stationary, type 1G | 616389 |
| congenital stationary night blindness autosomal dominant 3 | Alliance | Night blindness, congenital stationary, autosomal dominant 3 | 610444 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | G-protein alpha subunit, group I | G protein alpha subunit, helical insertion | Guanine nucleotide binding protein, alpha subunit | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|
| UniProtKB:Q90WX6 | InterPro | 350 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers