ZFIN is now using GRCz12tu for Genomic Data
Gene
dmbx1a
- ID
- ZDB-GENE-020117-1
- Name
- diencephalon/mesencephalon homeobox 1a
- Symbol
- dmbx1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in brain development; eye development; and negative regulation of DNA-templated transcription. Acts upstream of or within several processes, including midbrain development; regulation of neural retina development; and retina development in camera-type eye. Predicted to be located in nucleus. Is expressed in several structures, including anterior neural keel; anterior neural rod; brain; eye; and presumptive diencephalon. Orthologous to human DMBX1 (diencephalon/mesencephalon homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 25 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Wong et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Diencephalon/mesencephalon homeobox | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | OAR domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:A4IG24 | InterPro | 383 | |||||
| UniProtKB:Q8JI10 | InterPro | 388 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dmbx1a-201
(1)
|
Ensembl | 2,731 nt | ||
| mRNA |
dmbx1a-202
(1)
|
Ensembl | 2,663 nt | ||
| mRNA |
dmbx1a-203
(1)
|
Ensembl | 4,226 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers