Gene
aurkb
- ID
- ZDB-GENE-020419-40
- Name
- aurora kinase B
- Symbol
- aurkb Nomenclature History
- Previous Names
-
- aurB (1)
- cei
- cellular island
- CHUNP6896
- fa09g06
- fd02h12
- stka
- wu:fa09g06
- wu:fd02h12
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within chromosome segregation; cytoskeleton-dependent cytokinesis; and microtubule cytoskeleton organization. Predicted to be located in chromosome, centromeric region and spindle. Predicted to be part of chromosome passenger complex. Predicted to be active in several cellular components, including kinetochore; microtubule cytoskeleton; and midbody. Is expressed in several structures, including blastomere; blood; branchial mesenchyme; central nervous system; and proliferative region. Human ortholog(s) of this gene implicated in spermatogenic failure 5. Orthologous to several human genes including AURKB (aurora kinase B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85918 (18 images)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Aurora kinase-like | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
| UniProtKB:F1RDC1 | InterPro | 320 | |||||
| UniProtKB:Q6NW76 | InterPro | 320 |
Interactions and Pathways
No data available
Plasmids
No data available