ZFIN is now using GRCz12tu for Genomic Data
Gene
socs3a
- ID
- ZDB-GENE-030131-7349
- Name
- suppressor of cytokine signaling 3a
- Symbol
- socs3a Nomenclature History
- Previous Names
-
- socs3
- fj09e12
- wu:fj09e12
- zgc:56537 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cytokine receptor binding activity. Acts upstream of or within several processes, including hepatocyte differentiation; negative regulation of axon regeneration; and sensory system development. Is expressed in eye; female organism; lateral line; liver; and male organism. Human ortholog(s) of this gene implicated in obesity. Orthologous to human SOCS3 (suppressor of cytokine signaling 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 26 figures from 23 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56537 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | SH2 domain | SH2 domain superfamily | SOCS3, SH2 domain | SOCS box domain | SOCS box-like domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q7ZUC6 | InterPro | 207 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
socs3a-201
(1)
|
Ensembl | 1,935 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-socs3a | polyclonal | Rabbit |
|
1 |
Plasmids
No data available
- Genome Browsers