ZFIN is now using GRCz12tu for Genomic Data

Gene

xirp2b

ID

ZDB-GENE-030521-26

Name

xin actin binding repeat containing 2b

Symbol

xirp2b Nomenclature History

Previous Names

xirp2l
sb:cb526
Xin betaNA (1)

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to colocalize with focal adhesion and stress fiber. Is expressed in myotome; skeletal muscle; slow muscle cell; somite; and somite border. Human ortholog(s) of this gene implicated in depressive disorder. Orthologous to human XIRP2 (xin actin binding repeat containing 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb526 (18 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With xirp2b Human Ortholog

No data available

Associated With xirp2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR030072	Xin actin-binding repeat-containing protein 1/2
Repeat	IPR012510	Actin-binding, Xin repeat

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:F1QP52	InterPro	3250
UniProtKB:A0AB32TYR5	InterPro	3277
UniProtKB:A0ACD6B6A5	InterPro	3250
UniProtKB:A0AC58GHQ2	InterPro	3288
UniProtKB:A0AC58GHT2	InterPro	3315

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	xirp2b-201 (1) Ensembl	Ensembl	10,131 nt	Select Tool ZFIN BLAST
mRNA	xirp2b-202 (1) Ensembl	Ensembl	5,431 nt	Select Tool ZFIN BLAST
mRNA	xirp2b-203 (1) Ensembl	Ensembl	770 nt	Select Tool ZFIN BLAST
mRNA	xirp2b-205 (1) Ensembl	Ensembl	12,933 nt	Select Tool ZFIN BLAST
mRNA	xirp2b-206 (1) Ensembl	Ensembl	12,694 nt	Select Tool ZFIN BLAST
ncRNA	xirp2b-003 (1) Ensembl	Ensembl	352 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-xirp2b	polyclonal	xirp2b		Rabbit			1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations