ZFIN is now using GRCz12tu for Genomic Data
Gene
itgb1b
- ID
- ZDB-GENE-030909-10
- Name
- integrin, beta 1b
- Symbol
- itgb1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables protein heterodimerization activity. Involved in cell adhesion mediated by integrin and endothelial cell-matrix adhesion via fibronectin. Acts upstream of or within several processes, including Kupffer's vesicle development; cell migration involved in gastrulation; and striated muscle cell development. Predicted to be located in several cellular components, including lamellipodium; melanosome; and ruffle membrane. Predicted to be part of integrin complex. Predicted to be active in cell surface; focal adhesion; and synapse. Is expressed in several structures, including cardiovascular system; digestive system; mesoderm; muscle; and pleuroperitoneal region. Orthologous to human ITGB1 (integrin subunit beta 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 27 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb810 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 27 figures from 9 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002369 | Integrin beta subunit, VWA domain |
| Domain | IPR012896 | Integrin beta subunit, tail |
| Domain | IPR014836 | Integrin beta subunit, cytoplasmic domain |
| Domain | IPR016201 | PSI domain |
| Domain | IPR033760 | Integrin beta N-terminal |
| Domain | IPR040622 | Integrin beta, epidermal growth factor-like domain 1 |
| Family | IPR015812 | Integrin beta subunit |
| Homologous_superfamily | IPR032695 | Integrin domain superfamily |
| Homologous_superfamily | IPR036349 | Integrin beta tail domain superfamily |
| Homologous_superfamily | IPR036465 | von Willebrand factor A-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Integrin beta, epidermal growth factor-like domain 1 | Integrin beta N-terminal | Integrin beta subunit | Integrin beta subunit, cytoplasmic domain | Integrin beta subunit, tail | Integrin beta subunit, VWA domain | Integrin beta tail domain superfamily | Integrin domain superfamily | PSI domain | von Willebrand factor A-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IR57 | InterPro | 516 | ||||||||||
| UniProtKB:Q3YAA0 | InterPro | 795 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
itgb1b-201
(1)
|
Ensembl | 1,563 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-itgb1b | polyclonal |
|
1 |
Plasmids
No data available
- Genome Browsers