ddx27

ID

ZDB-GENE-031001-8

Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 27

Symbol

ddx27 Nomenclature History

Previous Names

cb843 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and nucleic acid binding activity. Acts upstream of or within rRNA processing. Predicted to be active in nucleolus. Is expressed in several structures, including alar plate midbrain region; brain; digestive system; musculature system; and retina. Orthologous to human DDX27 (DEAD-box helicase 27).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb843 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 8 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ddx27 Human Ortholog

No data available

Associated With ddx27 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR000629	ATP-dependent RNA helicase DEAD-box, conserved site
Domain	IPR001650	Helicase, C-terminal domain-like
Domain	IPR011545	DEAD/DEAH box helicase domain
Domain	IPR014001	Helicase superfamily 1/2, ATP-binding domain
Domain	IPR014014	RNA helicase, DEAD-box type, Q motif
Family	IPR050079	DEAD box RNA helicase
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase