ZFIN is now using GRCz12tu for Genomic Data
Gene
pxna
- ID
- ZDB-GENE-040105-1
- Name
- paxillin a
- Symbol
- pxna Nomenclature History
- Previous Names
-
- pxn
- wu:fw71f12
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable metal ion binding activity. Acts upstream of or within myotome development; skeletal muscle tissue development; and somitogenesis. Predicted to be located in anchoring junction; cell cortex; and cytoskeleton. Predicted to be active in cell-cell junction and focal adhesion. Is expressed in several structures, including Kupffer's vesicle; eye; myotome; notochord posterior region; and somite. Orthologous to human PXN (paxillin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Leupaxin/Paxillin/TGFB1I1 | Paxillin, Lim domain 2 | Paxillin, Lim domain 4 | Paxillin/TGFB1I1, LIM domain 1 | Zinc finger, LIM-type |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q6R3L1 | InterPro | 533 | |||||
| UniProtKB:A0AC58JI47 | InterPro | 953 | |||||
| UniProtKB:A0AC58JI49 | InterPro | 1063 | |||||
| UniProtKB:A0AC58JI50 | InterPro | 1240 | |||||
| UniProtKB:A0AC58JI51 | InterPro | 578 | |||||
| UniProtKB:A0AC58JI52 | InterPro | 710 | |||||
| UniProtKB:A0AC58JI54 | InterPro | 423 | |||||
| UniProtKB:A0AC58JI58 | InterPro | 423 | |||||
| UniProtKB:A0AC58JI75 | InterPro | 423 |
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-pxn | monoclonal | IgG1 | Mouse |
|
BD Biosciences
|
10 |
Plasmids
No data available
- Genome Browsers