saga

ID

ZDB-GENE-040426-1538

Name

S-antigen; retina and pineal gland (arrestin) a

Symbol

saga Nomenclature History

Previous Names

Arrestin Sa (1)
DrArr-R1 (1)
fk56b01
rod arrestin (1)
wu:fk56b01
zgc:66109
zgc:85885 (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable G protein-coupled receptor binding activity. Predicted to be involved in G protein-coupled receptor internalization. Predicted to act upstream of or within signal transduction. Predicted to be active in photoreceptor inner segment and photoreceptor outer segment. Is expressed in epiphysis; retina; and retinal outer nuclear layer. Human ortholog(s) of this gene implicated in Oguchi disease-1; hereditary night blindness; retinitis pigmentosa; and retinitis pigmentosa 47. Orthologous to human SAG (S-antigen visual arrestin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:85885 (16 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With saga Human Ortholog

No data available

Associated With saga Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR011021	Arrestin-like, N-terminal
Domain	IPR011022	Arrestin C-terminal-like domain
Family	IPR000698	Arrestin
Homologous_superfamily	IPR014752	Arrestin-like, C-terminal
Homologous_superfamily	IPR014753	Arrestin, N-terminal
Homologous_superfamily	IPR014756	Immunoglobulin E-set