matn1

ID

ZDB-GENE-050307-3

Name

matrilin 1

Symbol

matn1 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable calcium ion binding activity. Acts upstream of or within cartilage development. Predicted to be located in extracellular region. Predicted to be active in collagen-containing extracellular matrix. Is expressed in several structures, including cartilage element; head; integument; notochord; and pectoral fin. Orthologous to human MATN1 (matrilin 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 8 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Neacsu et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With matn1 Human Ortholog

No data available

Associated With matn1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000742	EGF-like domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR002035	von Willebrand factor, type A
Domain	IPR019466	Matrilin, coiled-coil trimerisation domain
Family	IPR050525	Extracellular Matrix Assembly and Organization
Homologous_superfamily	IPR036337	Matrilin, coiled-coil domain superfamily
Homologous_superfamily	IPR036465	von Willebrand factor A-like domain superfamily