ZFIN is now using GRCz12tu for Genomic Data
Gene
tcf21
- ID
- ZDB-GENE-051113-88
- Name
- transcription factor 21
- Symbol
- tcf21 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; E-box binding activity; and protein dimerization activity. Acts upstream of or within artery development and branchiomeric skeletal muscle development. Located in nucleus. Is expressed in cardiovascular system; head muscle; mesenchymal cell; mesoderm; and pharyngeal arch. Human ortholog(s) of this gene implicated in coronary artery disease and ventricular septal defect. Orthologous to human TCF21 (transcription factor 21).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 38 figures from 21 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | E-box Binding Transcriptional Regulators | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain |
|---|---|---|---|---|---|
| UniProtKB:Q32PV5 | InterPro | 176 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers