ZFIN is now using GRCz12tu for Genomic Data
Gene

alg13

ID
ZDB-GENE-060307-1
Name
ALG13 UDP-N-acetylglucosaminyltransferase subunit
Symbol
alg13 Nomenclature History
Previous Names
  • otud4 (1)
  • otul
  • z-otu (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to enable K63-linked deubiquitinase activity and cysteine-type deubiquitinase activity. Acts upstream of or within dorsal/ventral pattern formation. Predicted to be located in endoplasmic reticulum membrane. Is expressed in blastodisc; ovary; unfertilized egg; and yolk. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 36. Orthologous to human ALG13 (ALG13 UDP-N-acetylglucosaminyltransferase subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Tse et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With alg13 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
developmental and epileptic encephalopathy 36 Alliance Developmental and epileptic encephalopathy 36 300884
Associated With alg13 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002999 Tudor domain
Domain IPR003323 OTU domain
Domain IPR047387 Bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13, OTU domain
Family IPR050704 Peptidase C85-like
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Additional Resources Length Bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13, OTU domain OTU domain Papain-like cysteine peptidase superfamily Peptidase C85-like Tudor domain
UniProtKB:E9QIU2 InterPro 889
UniProtKB:A0A0R4IPL2 InterPro 854
UniProtKB:Q49HH8 InterPro 859
UniProtKB:A0AB32T7W6 InterPro 890
UniProtKB:A0AB32T982 InterPro 856
UniProtKB:A0AB32T9M6 InterPro 855
UniProtKB:A0AB32TAE8 InterPro 854
UniProtKB:A0AB32TAQ8 InterPro 889
UniProtKB:A0AB32TDG3 InterPro 888
UniProtKB:A0AB32TFB2 InterPro 736
UniProtKB:A0AC58I976 InterPro 893
UniProtKB:A0AC58I980 InterPro 894
UniProtKB:A0AC58I982 InterPro 892
UniProtKB:A0AC58I983 InterPro 893
UniProtKB:A0AC58I984 InterPro 889
UniProtKB:A0AC58I985 InterPro 893
UniProtKB:A0AC58I986 InterPro 891
UniProtKB:A0AC58I987 InterPro 892
UniProtKB:A0AC58I990 InterPro 892
UniProtKB:A0AC58I991 InterPro 859
UniProtKB:A0AC58I992 InterPro 888
UniProtKB:A0AC58I993 InterPro 859
UniProtKB:A0AC58I994 InterPro 858
UniProtKB:A0AC58I995 InterPro 888
UniProtKB:A0AC58I996 InterPro 860
UniProtKB:A0AC58I997 InterPro 857
UniProtKB:A0AC58I998 InterPro 887
UniProtKB:A0AC58I9A0 InterPro 858
UniProtKB:A0AC58I9A1 InterPro 858
UniProtKB:A0AC58I9A2 InterPro 859
UniProtKB:A0AC58I9A3 InterPro 855
UniProtKB:A0AC58I9A4 InterPro 855
UniProtKB:A0AC58I9A5 InterPro 824
UniProtKB:A0AC58I9A6 InterPro 822
UniProtKB:A0AC58I9A7 InterPro 858
UniProtKB:A0AC58I9A8 InterPro 854
UniProtKB:A0AC58I9A9 InterPro 853
UniProtKB:A0AC58I9B0 InterPro 855
UniProtKB:A0AC58I9B1 InterPro 821
UniProtKB:A0AC58I9B3 InterPro 854
UniProtKB:A0AC58I9B4 InterPro 825
UniProtKB:A0AC58I9B6 InterPro 853
UniProtKB:A0AC58I9B7 InterPro 824
UniProtKB:A0AC58I9B8 InterPro 823
UniProtKB:A0AC58I9C0 InterPro 820
UniProtKB:A0AC58I9C1 InterPro 820
UniProtKB:A0AC58I9C2 InterPro 819
UniProtKB:A0AC58I9C3 InterPro 820
UniProtKB:A0AC58I9C5 InterPro 819
UniProtKB:A0AC58I9C6 InterPro 819
UniProtKB:A0AC58I9D3 InterPro 818
UniProtKB:A0ACD6B610 InterPro 889
UniProtKB:A0ACD6B7H7 InterPro 854
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA alg13-201 (1) Ensembl 2,837 nt
mRNA alg13-202 (1) Ensembl 2,820 nt
mRNA alg13-203 (1) Ensembl 2,711 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-alg13 polyclonal Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations