Gene
myo18aa
- ID
- ZDB-GENE-080425-5
- Name
- myosin XVIIIAa
- Symbol
- myo18aa Nomenclature History
- Previous Names
-
- myo18b (1)
- myo18l2
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity. Acts upstream of or within Golgi organization; cell-matrix adhesion; and striated muscle cell development. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm and myosin filament. Is expressed in somite border. Orthologous to human MYO18A (myosin XVIIIA).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Cao et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Cao et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR000048 | IQ motif, EF-hand binding site |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR001609 | Myosin head, motor domain-like |
| Domain | IPR036064 | Class XVIII myosin, motor domain |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
| Homologous_superfamily | IPR036961 | Kinesin motor domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Class XVIII myosin, motor domain | IQ motif, EF-hand binding site | Kinesin motor domain superfamily | Myosin head, motor domain-like | PDZ domain | PDZ superfamily | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB32TWF4 | InterPro | 2068 | |||||||
| UniProtKB:A0AB32TYT0 | InterPro | 2489 | |||||||
| UniProtKB:A0AB32TZN2 | InterPro | 2482 | |||||||
| UniProtKB:A0AB32U1J8 | InterPro | 2480 | |||||||
| UniProtKB:A0AB32U1Y3 | InterPro | 2160 | |||||||
| UniProtKB:A0AB32U2R9 | InterPro | 2472 | |||||||
| UniProtKB:A0AB32U2V6 | InterPro | 2504 | |||||||
| UniProtKB:A0AB32U2X2 | InterPro | 2083 | |||||||
| UniProtKB:A0AB32U3Z3 | InterPro | 2450 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
myo18aa-201
(1)
|
Ensembl | 7,287 nt | ||
| mRNA |
myo18aa-202
(1)
|
Ensembl | 8,585 nt |
Interactions and Pathways
No data available
Plasmids
No data available