ZFIN is now using GRCz12tu for Genomic Data
Gene
col22a1
- ID
- ZDB-GENE-090827-2
- Name
- collagen, type XXII, alpha 1
- Symbol
- col22a1 Nomenclature History
- Previous Names
-
- col9a1 (1)
- prp
- Type
- protein_coding_gene
- Location
- Ambiguous Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be an extracellular matrix structural constituent conferring tensile strength. Acts upstream of or within several processes, including embryonic caudal fin morphogenesis; fin regeneration; and muscle attachment. Predicted to be located in extracellular region. Predicted to be part of collagen trimer. Predicted to be active in basement membrane. Is expressed in several structures, including head; heart; inner ear; myotome; and pectoral fin. Human ortholog(s) of this gene implicated in intracranial aneurysm. Orthologous to human COL22A1 (collagen type XXII alpha 1 chain).
- Genome Resources
-
- Alliance (1)
- Gene:100317029 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 17 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002035 | von Willebrand factor, type A |
| Domain | IPR048287 | Thrombospondin-like, N-terminal domain |
| Family | IPR050149 | Collagen superfamily |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR036465 | von Willebrand factor A-like domain superfamily |
| Repeat | IPR008160 | Collagen triple helix repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | Collagen superfamily | Collagen triple helix repeat | Concanavalin A-like lectin/glucanase domain superfamily | Thrombospondin-like, N-terminal domain | von Willebrand factor A-like domain superfamily | von Willebrand factor, type A |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IR54 | InterPro | 1622 | ||||||
| UniProtKB:M5BFV8 | InterPro | 1622 | ||||||
| UniProtKB:A0AC58HX50 | InterPro | 1534 | ||||||
| UniProtKB:A0AC58HX53 | InterPro | 1573 | ||||||
| UniProtKB:A0AC58HX61 | InterPro | 1622 |
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-col22a1 | polyclonal | Rabbit |
|
3 |
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance