Gene
rptor
- ID
- ZDB-GENE-130530-685
- Name
- regulatory associated protein of MTOR, complex 1
- Symbol
- rptor Nomenclature History
- Previous Names
-
- zmp:0000000682 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in several processes, including TORC1 signaling; cellular response to amino acid stimulus; and positive regulation of cell growth. Predicted to act upstream of or within TOR signaling. Predicted to be part of TORC1 complex. Predicted to be active in cytoplasm. Is expressed in head; notochord; post-vent region; pronephros; and spinal cord. Human ortholog(s) of this gene implicated in nicotine dependence. Orthologous to human RPTOR (regulatory associated protein of MTOR complex 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR029347 | Raptor, N-terminal CASPase-like domain |
| Family | IPR004083 | Regulatory associated protein of TOR |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR000357 | HEAT repeat |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | Armadillo-like helical | Armadillo-type fold | HEAT repeat | Raptor, N-terminal CASPase-like domain | Regulatory associated protein of TOR | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IFI0 | InterPro | 1363 | ||||||||
| UniProtKB:A0A8M6Z171 | InterPro | 1350 | ||||||||
| UniProtKB:A0AB32TLR5 | InterPro | 1108 |
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-rptor | monoclonal | Rabbit |
|
Cell Signaling Technology, Inc.
|
3 |
Plasmids
No data available