ZFIN is now using GRCz12tu for Genomic Data
Gene
piezo2b
- ID
- ZDB-GENE-130530-810
- Name
- piezo-type mechanosensitive ion channel component 2b
- Symbol
- piezo2b Nomenclature History
- Previous Names
-
- piezo2
- zmp:0000000807 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable mechanosensitive monoatomic ion channel activity. Acts upstream of or within thigmotropism. Predicted to be located in plasma membrane. Predicted to be active in nucleus. Is expressed in Rohon-Beard neurons; olfactory epithelium; taste bud; and trigeminal ganglion.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Faucherre et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| distal arthrogryposis type 3 | Alliance | Arthrogryposis, distal, type 3 | 114300 |
| distal arthrogryposis type 5 | Alliance | Arthrogryposis, distal, type 5 | 108145 |
| Arthrogryposis, distal, with impaired proprioception and touch | 617146 | ||
| ?Marden-Walker syndrome | 248700 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Piezo family | Piezo non-specific cation channel, cap domain | Piezo, TM25-28 |
|---|---|---|---|---|---|
| UniProtKB:A0A8M9P2A0 | InterPro | 2972 | |||
| UniProtKB:A0A8M9PNY5 | InterPro | 2984 | |||
| UniProtKB:A0A8M9PS85 | InterPro | 3005 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
piezo2b-201
(1)
|
Ensembl | 1,764 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-piezo2 | polyclonal | IgG | Rabbit |
|
Life Technologies (Invitrogen)
|
3 |
Plasmids
No data available
- Genome Browsers