ZFIN is now using GRCz12tu for Genomic Data
Gene
prox1a
- ID
- ZDB-GENE-980526-397
- Name
- prospero homeobox 1a
- Symbol
- prox1a Nomenclature History
- Previous Names
-
- prox1 (1)
- zgc:111888
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including lymphangiogenesis; negative regulation of DNA-binding transcription factor activity; and neuromast development. Located in nucleus. Is expressed in several structures, including digestive system; mesoderm; nervous system; pleuroperitoneal region; and trunk vasculature. Orthologous to human PROX1 (prospero homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 187 figures from 121 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu351 (26 images)
Wild Type Expression Summary
- All Phenotype Data
- 13 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeo-prospero domain | Homeo-prospero domain superfamily | Prospero homeodomain family |
|---|---|---|---|---|---|---|
| UniProtKB:Q90ZL7 | InterPro | 739 | ||||
| UniProtKB:F1QAE1 | InterPro | 739 | ||||
| UniProtKB:A0AB32T7B8 | InterPro | 740 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prox1a-201
(1)
|
Ensembl | 3,008 nt | ||
| mRNA |
prox1a-202
(1)
|
Ensembl | 2,814 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab4-prox1 | polyclonal | IgG | Goat |
|
R&D Systems
|
7 | |
| Ab5-prox1 | polyclonal | IgG | Rabbit |
|
AngioBio
|
27 | |
| Ab7-prox1 | polyclonal | Rabbit |
|
RELIA Tech
|
5 | ||
| Ab2-Prox1 | polyclonal | Rabbit |
|
3 | |||
| Ab6-prox1 | polyclonal | Rabbit |
|
7 | |||
| Ab3-prox1 | polyclonal | Rabbit |
|
Millipore
|
52 |
Plasmids
No data available
- Genome Browsers