ZFIN is now using GRCz12tu for Genomic Data
Gene
mef2aa
- ID
- ZDB-GENE-990415-163
- Name
- myocyte enhancer factor 2aa
- Symbol
- mef2aa Nomenclature History
- Previous Names
-
- mef2a
- etID309779.18 (1)
- wu:fd19d02
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables transcription cis-regulatory region binding activity. Acts upstream of or within several processes, including myofibril assembly; positive regulation of macromolecule biosynthetic process; and somitogenesis. Predicted to be located in nucleus. Is expressed in cardiovascular system; myotome; nervous system; pharyngeal arch; and somite. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human MEF2A (myocyte enhancer factor 2A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55208 (13 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| coronary artery disease | Alliance | {Coronary artery disease, autosomal dominant, 1} | 608320 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Holliday junction regulator protein family C-terminal | MADS MEF2-like, N-terminal | Transcription factor, MADS-box | Transcription factor, MADS-box superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PPZ2 | InterPro | 466 | ||||
| UniProtKB:A0A0R4IRM3 | InterPro | 460 | ||||
| UniProtKB:Q1LXH6 | InterPro | 458 | ||||
| UniProtKB:A0A8M9P9W4 | InterPro | 467 | ||||
| UniProtKB:A0A8M2B5M2 | InterPro | 503 | ||||
| UniProtKB:A0A8M9PLW4 | InterPro | 511 | ||||
| UniProtKB:A0A8M2B5Z6 | InterPro | 504 | ||||
| UniProtKB:A0A8M9PF86 | InterPro | 512 | ||||
| UniProtKB:A0A8M9PF89 | InterPro | 467 | ||||
| UniProtKB:A0A8M9P0X9 | InterPro | 468 | ||||
| UniProtKB:A0AB32T6Z3 | InterPro | 513 | ||||
| UniProtKB:A0AB32T895 | InterPro | 512 | ||||
| UniProtKB:A0AB32T8F6 | InterPro | 469 | ||||
| UniProtKB:A0AB32T9S1 | InterPro | 468 | ||||
| UniProtKB:A0AB32TBP1 | InterPro | 468 | ||||
| UniProtKB:A0AB32TD81 | InterPro | 467 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mef2aa-201
(1)
|
Ensembl | 1,736 nt | ||
| mRNA |
mef2aa-202
(1)
|
Ensembl | 1,844 nt | ||
| mRNA |
mef2aa-204
(1)
|
Ensembl | 1,733 nt | ||
| mRNA |
mef2aa-205
(1)
|
Ensembl | 2,113 nt | ||
| mRNA |
mef2aa-206
(1)
|
Ensembl | 2,103 nt | ||
| mRNA |
mef2aa-207
(1)
|
Ensembl | 2,124 nt | ||
| mRNA |
mef2aa-208
(1)
|
Ensembl | 1,873 nt | ||
| mRNA |
mef2aa-209
(1)
|
Ensembl | 1,963 nt | ||
| ncRNA |
mef2aa-005
(1)
|
Ensembl | 606 nt |
Interactions and Pathways
No data available
Plasmids
- Genome Browsers