ZFIN is now using GRCz12tu for Genomic Data
Gene
eef1a1l1
- ID
- ZDB-GENE-990415-52
- Name
- eukaryotic translation elongation factor 1 alpha 1, like 1
- Symbol
- eef1a1l1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable GTPase activity and translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to be located in cytoplasm. Is expressed in several structures, including integument; musculature system; nervous system; pleuroperitoneal region; and skeletal system.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 63 figures from 46 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6910540 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR031157 | Tr-type G domain, conserved site |
| Domain | IPR000795 | Translational (tr)-type GTP-binding domain |
| Domain | IPR004161 | Translation elongation factor EFTu-like, domain 2 |
| Domain | IPR054696 | GTP-eEF1A, C-terminal domain |
| Family | IPR004539 | Translation elongation factor EF1A, eukaryotic/archaeal |
| Family | IPR050100 | Translation factor GTPase superfamily members |
| Homologous_superfamily | IPR009000 | Translation protein, beta-barrel domain superfamily |
| Homologous_superfamily | IPR009001 | Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | GTP-eEF1A, C-terminal domain | P-loop containing nucleoside triphosphate hydrolase | Translational (tr)-type GTP-binding domain | Translation elongation factor EF1A, eukaryotic/archaeal | Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal | Translation elongation factor EFTu-like, domain 2 | Translation factor GTPase superfamily members | Translation protein, beta-barrel domain superfamily | Tr-type G domain, conserved site |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q92005 | InterPro | 462 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
eef1a1l1-201
(1)
|
Ensembl | 1,745 nt | ||
| mRNA |
eef1a1l1-202
(1)
|
Ensembl | 4,216 nt | ||
| mRNA |
eef1a1l1-203
(1)
|
Ensembl | 4,455 nt | ||
| mRNA |
eef1a1l1-204
(1)
|
Ensembl | 4,455 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-eef1a1l1 | polyclonal | IgG | Rabbit |
|
GeneTex
|
3 |
Plasmids
- Genome Browsers
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- Sultmann, et al, 2000. (ZDB-PUB-001220-4) report orthology of this gene to human EF1A (now EEF1A1) based on amino acid similarity and conserved location. Subsequent analysis suggests eef1a1a (ZDB-GENE-030131-8278) and eef1a1b (ZDB-GENE-050417-327) are the orthologous genome duplicates of human EEF1A1 and mouse Eef1a1 based on amino acid similarity and conserved location.