Gene
opn1sw1
- ID
- ZDB-GENE-991109-25
- Name
- opsin 1 (cone pigments), short-wave-sensitive 1
- Symbol
- opn1sw1 Nomenclature History
- Previous Names
-
- SWS1 (1)
- uvops
- zfuv
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and detection of light stimulus. Predicted to be located in membrane. Predicted to be active in photoreceptor outer segment and plasma membrane. Is expressed in several structures, including digestive system; endocrine system; heart; photoreceptor cell; and visual system. Human ortholog(s) of this gene implicated in blue color blindness. Orthologous to human OPN1SW (opsin 1, short wave sensitive).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 93 figures from 64 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73050 (2 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Yoshimatsu et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| blue color blindness | Alliance | Colorblindness, tritan | 190900 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR027430 | Visual pigments (opsins) retinal binding site |
| Domain | IPR017452 | GPCR, rhodopsin-like, 7TM |
| Family | IPR000276 | G protein-coupled receptor, rhodopsin-like |
| Family | IPR001521 | Opsin, blue sensitive |
| Family | IPR001760 | Opsin |
| Family | IPR050125 | G-protein coupled receptor opsins |
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G-protein coupled receptor opsins | G protein-coupled receptor, rhodopsin-like | Opsin | Opsin, blue sensitive | Visual pigments (opsins) retinal binding site |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q9W6A9 | InterPro | 336 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
opn1sw1-201
(1)
|
Ensembl | 1,777 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab2-opn1sw1 |
|
ABclonal
|
1 | ||||
| Ab1-opn1sw1 | polyclonal | Rabbit |
|
43 |
Plasmids
No data available