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Fig. 4 Vertebral fusions occur in the absence of gross notochord patterning and segmentation defects. Alternating domains of entpd5a and col9a2 positive cells are present and appear normal in both WT (left) and col11a2del/del mutant (right) embryos at 5.5 mm SL, prior to the onset of fusions (top). At the onset of fusions (6 mm SL; bottom), ectopic entpd5a positive cells are present in the previously cartilaginous domains of col11a2del/del mutant animals (arrowheads). These cells are also weakly col9a2 positive.
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Full text @ Hum. Mol. Genet.