FIGURE

Fig. 4

ID
ZDB-FIG-231228-153
Publication
Rebello et al., 2023 - COL11A2 as a candidate gene for vertebral malformations and congenital scoliosis
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Fig. 4

Vertebral fusions occur in the absence of gross notochord patterning and segmentation defects. Alternating domains of entpd5a and col9a2 positive cells are present and appear normal in both WT (left) and col11a2del/del mutant (right) embryos at 5.5 mm SL, prior to the onset of fusions (top). At the onset of fusions (6 mm SL; bottom), ectopic entpd5a positive cells are present in the previously cartilaginous domains of col11a2del/del mutant animals (arrowheads). These cells are also weakly col9a2 positive.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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