IMAGE

Figure 6.

ID
ZDB-IMAGE-250130-45
Source
Figures for Liu et al., 2023
Image
Figure Caption

Figure 6.

A schematic diagram showing the regulatory mechanism, whereby TMEM88 promotes PPP specification through suppressing Wnt/β-catenin signaling. The deficiency of tmem88a/b leads to an excessive accumulation of β-catenin in both the cytoplasm and nucleus of pharyngeal endodermal cells that are intended to differentiate into PPPs, thereby resulting in hyperactivation of Wnt signaling and defects in PPP specification.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Life Med