ZFIN Image: Kawahara et al., 2025, FIGURE 2

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Figure Caption

FIGURE 2

Establishment of adap1 mutants. (a) Molecular structure of adap1. The ArfGAP, pleckstrin homology 1 (PH1) and PH2 domains in the Adap1 protein are indicated by the red, green, and blue rectangles, respectively. The adap1‐uy70 and adap1‐uy71 mutants contained premature stop codons after 24 missense amino acids starting at amino acid 125 and after 30 missense amino acids starting at amino acid 118, respectively. (b–d) Morphology of the wild‐type (b), adap1^uy70/uy70 mutant (c), and adap1^uy71/uy71 mutant (d) zebrafish. Scale bar, 500 μm (b). Genotyping of individual embryos was performed by genomic PCR.

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Phenotype details

Acknowledgments

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