Fig. 5 CUT&Tag of Znf706 in stage I oocytes. A: Schematic showing collection of stage I oocyte for CUT&Tag of Znf706 and stage I and II oocytes for RNA-seq. B: Venn diagrams illustrating the overlap between Znf706 and IgG CUT&Tag (left) and a pie chart showing the distribution of Znf706 peaks at promoter and distal regions (right). C: Heatmap showing the Znf706 in WT and znf706−/− oocytes and IgG in WT oocytes enrichment around peak center (peak center ± 2 kb). D: Bar plot showing GO analysis of 255 genes bound by Znf706 at the promoter regions. E: UCSC Genome Browser snapshots showing Znf706 and IgG peaks at promoter regions of eif4a3, brd3b, ncl, and arid4a. Pink shadows indicated promoter regions. WT, wild-type; st., stage; C&T, CUT&Tag.
Reprinted from Journal of genetics and genomics = Yi chuan xue bao, 52, Zhang, W., Li, Y., Li, H., Liu, X., Zheng, T., Li, G., Liu, B., Lv, T., Wei, Z., Xing, C., Jia, S., Meng, A., Wu, X., Znf706 regulates germ plasm assembly and primordial germ cell development in zebrafish, 666-679, Copyright (2024) with permission from Elsevier. Full text @ J. Genet. Genomics